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Home >> FcRn and Apoptosis Dynamics >> Rituxan

Rituxan alone induces apoptosis while 1F5 and 2H7 require GAM mediated hyper-crosslinking (Ramos B cells analyzed by flow cytometry after 18-22 hours)

Ref.16 from previous slide: Hofmeister et al. Clustered CD20 Induced Apoptosis: Src-Family Kinase, the Proximal Regulator of Tyrosine Phosphorylation, Calcium Influx, and Caspase 3-Dependent Apoptosis, Blood Cells, Molecules, and Diseases (2000) 26, 133-143.