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Home >> FcRn and Apoptosis Dynamics >> p38 MAPK

p38 inhibitor decreases % apoptosis; MEK inhibitor has no effect on CD20 mediated apoptosis

Pedersen et al. The chimeric anti-CD20 antibody rituximab induces apoptosis in B-cell chronic lymphocytic leukemia cells through a p38 mitogen activated protein-kinase-dependent mechanism, Blood (2002) 99, 1314-1319