VISION-BIOMODBASE - Biocybernetics Lab, UCLA

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VISION-BIOMODBASE
Home >> PBPK >> Predict F(ab')2 Biodistribution

Change antibody specific parameters as listed in Baxter et al.

σ_L (osmotic reflection coeff. for large pores)
σ_S (osmotic reflection coeff. for small pores)
PS_L,organ (permeability-surface area product for large pores)
PS_S,organ (permeability-surface area product for small pores)
U (renal clearance – scaled from rat)

Allometric Scaling